Technology Platforms

Life sciences companies are increasingly outsourcing their discovery work and laboratory testing, and require an experienced and knowledgeable partner who can offer academic insight and seamless integration into clinical development operations. CirQuest Labs offers a comprehensive portfolio of technology platforms to accommodate virtually all of your technology testing requirements.

We provide clients with flexibility in choosing from assays which are either commercially available or developed by you or by our staff of experts. We can work with you to develop and validate a custom assay based on your discovery efforts and goals.

Our research team is headed by educated biologists and molecular scientists with drug discovery, biological assay, and disease target expertise. Our laboratories are fully equipped to provide a broad array of services including in vitro and ex vivo biology support and validation testing for drug discovery, cell and cell line testing, and antibody characterizations. A wide array of  services completes our vast array of laboratory services:

  • Biochemical assays (proteins, signaling pathways, intracellular and extracellular proteins, matrix remodeling and other biomarkers)

  • Cell-based assays using cells and cell lines (antigens, adhesion, motility, invasion, proliferation, apoptosis)

  • Assay technologies (ELISA, flow cytometry, multi-arrays, protein cascades)

  • SDS-PAGE and Western blot

  • Immunoassay and antibody characterization

  • Platelet function and coagulation

Screening, validation and characterization

  • Compound, peptide, and antibody assays

  • Molecular studies

  • Preclinical safety assays

Genetics and genomics

  • DNA and RNA isolation and storage

  • Gene expression

  • Quantitative PCR

Target validation

  • Molecular and cellular validation and in vitro proof-of-concept design and testing

  • Thrombosis and hemostasis

  • Cardiovascular, cerebrovascular and PAD

  • Hematology

  • Vascular bed diseases including metabolic syndromes

  • Inflammation

  • Tumor cell biology

  • Biocompatibility of devices and implantable materials